
Behind the Scenes at 5AM: Building Seed Companies from nothing
December 5, 2025
In this episode of Talent Therapy, Chris welcomes back Kori, a seasoned leader who has spent her entire career inside life sciences — from recruiting at Novartis to early-stage company-building at Relay Therapeutics, and now leading talent and HR within the venture ecosystem at 5AM Ventures.
Kori reflects on the evolution of her work and what surprised her about moving from “filling roles” to building companies from scratch. She highlights the thrilling — and humbling — process of identifying groundbreaking science, evaluating what deserves investment, and then assembling the human systems required to turn a promising idea into a living, breathing biotech company.
Underneath the technical layers is a very human theme: people make or break the science.
Even the strongest technology can fail without a founding team that is emotionally mature, collaborative, and willing to learn.
Kori shares lessons from working with founders — many of whom are deeply attached to their scientific inventions — and the compassionate conversations required to help them find the right role, the right timing, and sometimes the courage to let others carry the work forward.
She opens the curtain on 5AM’s venture creation engine, which supports startups from incorporation all the way to team building, budgeting, and scientific de-risking.
Her reflections remind us that company creation is messy, exhilarating, vulnerable work — and that success isn’t just about data; it’s about trust, humility, and shared purpose.
This is a story about science, but more than that, it’s a story about the people who decide to build something that could change lives.
Main points:
- People are the differentiator, not just the data.
Great science with a dysfunctional team rarely wins. - Emotional intelligence matters at the earliest stage.
Self-awareness, feedback skills, and humility are selection criteria — not “nice-to-haves.” - Founders often face an identity crossroads.
Letting go or shifting roles isn’t just a business decision — it can be deeply personal. - Company creation is equal parts science, planning, and empathy.
Investors don’t just evaluate ideas — they help shape people, process, and culture. - Support systems change trajectories.
Early-stage founders don’t need just capital — they need mentorship, structure, and partnership.
Hear more great guests: https://www.ronanvancesearch.com/podcast

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